Scientific program

Thursday September 11, 2025

8.55 – 9.00 Welcome and introduction to hospital and team (Roman Hajek)

9.00 – 9.15 Pre-meeting test (Faculty)

9.15 – 9.30 MGUS and SMM: diagnosis & treatment (Roman Hajek)

9.30 – 9.50 Treatment of newly diagnosed multiple myeloma - general overview (Roman Hajek)

9.50 – 10.20 Treatment of relapse/refractory multiple myeloma - general overview (Jana Mihalyova)

10.20 – 10.45 Coffee break

10.45 – 11.30 Patient cases discussions (Gabor Mikala/ László Váróczy)

11.30 – 12.30

LAB VISIT:

  • CAR - T preparation & genetic manipulation
  • Monitoring of immunocompetent cells using spectral flowcytometry

(Michal Simicek/Ondrej Venglar)

12.45 – 14.00 Lunch

14.00 – 14.30 Essential supportive treatment in modern immunotherapy (CAR-T, bispecific antibodies) (Jana Mihalyova)

14.30 – 15.00 Discussion 1: How to optimize drug dosing for long-term administration?

  • Dexamethasone
  • IMiDs and Proteasome inhibitors
  • Bispecific monoclonal antibodies

(Ludmila Muronova/Gergely Varga)

15.15 – 16.00 Discussion 2: How does MRD negativity status influence subsequent treatment decisions? (Szabolcs Modok/ Tomas Jelinek)

16.00 – 17.00 Work in the groups (All faculty)

17.00 Summary of Day 1

19.00 Dinner

Friday September 12, 2025

8.30 – 9.30 

Principle of biobanking; Selection of plasma cells with imunomagnetic separation (MACS) and/or with FACS (Lucie Broskevicova)

Novel genomics methods in multiple myeloma: how can we understand them? (Tereza Sevcikova)

Utility of multiparameter flow cytometry in plasma cell disorders (Diagnostic & CTc & MRD) (Tomas Jelinek/ Ondrej Venglar)

9.30 – 9.50 How to effectively organize clinical trials: an example of teamwork (tour of the clinical trial department and hematooncology department) (Ondrej Boncek/ Roman Hajek)

10.30 – 11.00 Coffee break

11.00 – 11.30 New definition of high-risk multiple myeloma: what to do in real life? (Roman Hajek/Gabor Mikala)

11.30 – 12.15 AL amyloidosis: diagnosis & treatment (Tomas Jelinek)

12.15 – 12.30 Role of real-life registry (Roman Hajek)

12.30 – 13.00 Post-meeting test; Summary of day 2 (Faculty)

13.00 Lunch